摘要
外切体是酿酒酵母中鉴定的一个保守复合体 ,具有 3′外切核酸酶的活性 .10个核心亚基 ,除Csl4p/Ski4p外 ,在体外都具有 3′外切核酸酶的活性 .外切体在多种RNA的代谢中起重要作用 .外切体普遍存在于真核生物中 ,并与真核基因的表达调控密切相关 .
The exosome is a conserved complex which identified in Saccharomyces cerevisiae and has 3' exoribonuclease activity in vitro. The exosome contains ten core subunits, and all except Csl4p/Ski4p are 3' exoribonucleases in vitro. The exosome acts important role in several pathways of RNA metabolism. The exosome is a universal complex in eukaryote and is related to expression of eukaryotic genes.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
2002年第1期10-13,共4页
Progress In Biochemistry and Biophysics
