基因打靶技术的研究进展

Progress of researches on the technology of gene targeting

基因打靶在人类遗传病动物模型的构建、基因治疗和基因功能研究等方面都有重要的作用。本文综述了一些常用的基因打靶策略 。

Gene targeting plays important role in the construction of animal models with human hereditary diseases,gene therapy and gene function resarches.The widely used strategies of gene targeting were reviewed,and progress of researches on these technologies was introduced.