喹赛多对鸡大肠杆菌病的预防效果研究

Preventive Effect of Kuisaiduo on Broilers with Escherichia coli

报道了药饲喹赛多对鸡人工感染大肠杆菌 (C84 0 10 )病的预防效果。接种前 5d开始用药 ,接种后连续用药 14d ,给药剂量如下 :喹乙醇组药物 2 5× 10 -6,喹赛多试验组药物 (× 10 -6)分别为 12 .5、2 5、5 0、10 0、2 0 0。结果表明 ,阴性对照组发病率达 80 % ,喹乙醇对照组发病率为 2 0 % ,而喹赛多 5 0× 10 -6、10 0× 10 -6、2 0 0× 10 -6组均将发病率控制在 10 %以内 ,明显优于喹乙醇组。且此 3组预防效果显著高于 12 .5× 10 -6、2 5× 10 -6组 ,增重效果极显著高于 12 .5× 10 -6、2 5× 10 -6组 (P <0 .0 1) ,而此 3组间差异不显著 (P >0 .0 5 )。由此可见 ,5 0× 10 -6以上的喹赛多不仅对人工诱发大肠杆菌病有明显预防效果 ,还可促进生长 ,提高饲料利用率。综合考虑 ,推荐 5 0× 10

The clinical preventible effect of kuisaiduo on broilers developed artificially with E.coli was studied.The broilers were feeded with medicated feed five days before the infection,and continued 14 days after the infection. The dosages were 25×10 -6 olaquindox in positive group,and 12.5 ×10 -6 ? 25×10 -6 ?50×10 -6 ?100×10 -6 ?200×10 -6 kuisaiduo in treated groups.The result showed that the incidences of disease in negaitive group and olaquindox group were 80% and 20% respectively,while the incidences of disease in 50×10 -6 ,100×10 -6 ,200×10 -6 groups were 10%,which were lower than that of olaquindox group. Moreover the preventible effect of 50×10 -6 ,100×10 -6 ,200×10 -6 groups were more significant than that of 12.5×10 -6 and 25×10 -6 groups . On the other hand, the weight gains of broilers in 50×10 -6 ?100×10 -6 ?200×10 -6 groups were higher than that of 12.5×10 -6 ?25×10 -6 groups significantly( P <0.01), whereas there were no statistic differences between these three groups ( P >0.05). These results showed that kuisaiduo at the level of 50×10 -6 ?100×10 -6 ?200×10 -6 can prevent colibacillosis efficiently,it can also improve the weight gain and efficiency of feed utilization at the same time. Taking the economic factor into the account, 50×10 -6 kuisaiduo in feeds is feasible for the clinical application.