二氧化碳浓度测量法在诊断睡眠呼吸暂停综合征中的应用研究

CLINICAL APPLICATION OF CAPNOGRAPHY IN DIAGNOSIS OF SLEEP APNEA SYNDROME

目的 同时采用热敏传感器和二氧化碳浓度测量仪监测睡眠呼吸暂停综合征 (SAS)患者 ,探讨二氧化碳浓度测量法在诊断SAS中的临床价值。方法 对 2 5例患者进行多导睡眠图和呼出气二氧化碳浓度描记图及呼气末二氧化碳分压 (PetCO2 )监测 ,并对PetCO2 值与呼吸紊乱指数 (AHI)的关系进行分析 ,统计方法采用t检验和相关分析。结果 以热敏传感器所得结果为标准 ,呼吸暂停、低通气和呼吸紊乱阳性诊断率分别为 84.5 %± 9.6 % ,72 .7%± 8.0 % ,81.2 %± 8.4% ;未发现假阳性。夜间平均PetCO2 和最高PetCO2 与窒息指数 (AI)、低通气指数(HI)、AHI均无显著相关性。结论 二氧化碳浓度测量法监测SAS具有较高的诊断率。

Objective\ To explore the clinical value of capnography in diagnosis of sleep apnea syndrome (SAS).Methods\ Polysomnography (PSG) and capnography monitoring were performed in 25 patients.The relation of end-tidal PCO_2(PetCO_2) with apnea-hypopnea index (AHI) were analysed.Results\ Compared with the results of thermistor,the positive ratio of apnea,hypopnea and apnea-hypopnea in the diagnosis of SAS was respectively 84.5%±9.6%,72.7%±8.0%,81.2%±8.4%.No false postive was found.The mean and highest nocturnal PetCO_2 weren't significantly correlated with apnea index (AI),hypopnea index (HI) and AHI.Conclusion\ Capnography is a sensitive and effective method in diagnosis of SAS.