不同降压药物对53例高血压病患者血浆纤维蛋白原的影响

EFFECTS OF DIFFERENT ANTIHYPERTENSIVE DRUGS ON PLASMA FIBRINOGEN IN 53 HYPERTENSIVE PATIENTS.

目的 探讨不同降压药物对高血压病患者血浆纤维蛋白原的影响。方法 采用免疫比浊法测定 5 3例高血压病患者经阿替洛尔、尼群地平或苯那普利降压治疗 6个月前、后血浆纤维蛋白原水平。结果 仅苯那普利降低纤维蛋白原。

Objectives: To investigate the effects of different antihypertensive drugs on plasma fibrinogen in essential hypertensive patients.Methods:53 essential hypertensive patients were randomly treated with Atenolol,Nitrendipine or Benazepril,turbidimetric immunoassay methods were used to evaluated plasma fibrinogen befor treatment and repeated after 6 months.Results: fibrinogen decrease after the treatment with benazepirl.Conclusions:It is suggested that angiotensin-converting enzyme inhibitor(ACEI) is effective antihypertensive medication for decrease plasma fibrinogen-an independent cardiovascular risk factor.