国内阿萨希毛孢子菌首次分离及鉴定

The First Isolation and Identification of Trichosporon Asahii in China

目的 首例报告国内Trichosporonasahii引起真菌病 ,并介绍此菌种的分离与鉴定。方法 从 1名未确诊女性患者受损皮肤 ,皮痂 ,口腔伪膜 ,阴道及口腔分泌物 ,尿便及肝穿刺组织 ,分离与培养出一种真菌 ,经生化分析 ,菌种鉴定分子生物学实验及DNA测序。结果证明此真菌为阿萨希毛孢子菌 (Trichosporonasahii) ,结论本文而诊断此患者罹患播散性真菌病 ,由此引起播散性真菌病在国内尚属首例报告。

Objective To report Trichosporon asahii first isolation and identification of TH chosporon asahii in chain.Methods A clinical infection fungus strain was isolaled from mouth pseudomembrane vaginal,nasal secretions,urine,faces,and live puncture tissue,injured skin tissue of a female patient,who had no clear underlying disease.Through cultured in medium,biochemical assay,identification of the bacterial race molecular biology test and DNA sequencing.Result We demostrated that the fungus strain was unanimously identified as Trichosporon asahii.Conclution The Trichosporon asahii could induce the disseminated Trichosporonosis.