乐果农药包装女工肺功能调查

Investigation on the pulmonary function in the female packers exposed to dimethoate

目的 了解有机磷农药对包装女工肺功能的影响。方法 对某农药厂 63名乐果包装女工进行班前、班后肺功能调查 ,同时进行空气中乐果浓度和女工全血胆碱酯酶测定。结果 ①包装女工胸闷、胸部紧束感明显高于对照组 ;②包装女工班后肺功能较班前明显下降 ,FEV1%班后异常率比班前明显增高 ;③大于 6年工龄的包装女工班后肺功能较班前明显下降 ;④包装女工班前、班后肺功能差值与年龄、工龄和全血胆碱酯酶呈正相关 ,而工龄与全血胆碱酯酶呈负相关。

Objective To understand the effects of organophosphorus pesticides on pulmonary function in the female packers. Methods The pulmonary functions were assessed in 63 female packers before and after work shifts in a certain pesticide factory and the concentration of dimethoate in the air and cholinesterase of the female workers were determined. Results ①Chest pain and feeling of pressure in the female packers were significantly higher than those in the controls. ②The pulmonary functions after work shifts were significantly lower than those before work shifts, and the abnormal rates of FEV 1 % after work shifts were significantly higher than that before work shifts. ③The pulmonary functions of the female packer sover 6 year workage were significantly lower after work shifts than before. ④The differences in observed values of the pulmonary function among female packers before and after work shifts were positively correlated with their age, working periods and concentration of cholinesterase, but the working periods were negatively correlated with cholinesterase. Conclusion It is concluded that the pulmonary functions could be injured to some extent in female packers exposed to organophosphorus pesticides.