大叶紫玉盘化学成分研究

STUDIES ON CHEMICAL CONSTITUENTS OF UVARIA MACROPHYLLA

目的 研究番荔枝科紫玉盘属植物大叶紫玉盘 (UvariamacrophyllaRoxb .)根的化学成分。方法 用硅胶色谱法分离化学成分 ,通过波谱方法 (IR ,UV ,EIMS ,1 HNMR ,1 3CNMR ,1 H 1 HCOSY ,HMQC ,NOESY ,HMBC)鉴定了他们的结构。结果 从氯仿的脱脂部分分离得到 7个化合物 ,其结构分别鉴定为 :大叶素 (1) ,onisyline (2 ) ,taraxerol (3) ,3,5 二甲氧基苄基苯甲酸酯 (4) ,苯甲酸 (5 ) ,β 谷甾醇 (6 )和胡萝卜苷 (7)。结论 大叶素为新化合物 ,其他

AIM To study the chemical constituents from Uvaria macrophylla Roxb. (Annonaceae). METHODS Various chromatography techniques were used to separate and purify the constituents. Their structures were elucidated by UV, IR, MS, 1HNMR , 13 CNMR , 1H 1H COSY, HMQC and HMBC spectral analysis. RESULTS Seven compounds have been isolated from the CHCl 3 extract of the roots of the U.macrophylla . They were identified as macrophyllin (1), onysilin (2), taraxerol (3), 3,5 dimethoxy benzyl benzoic acid ester (4), benzoic acid (5), β sitosterol (6) and daucosterol (7). CONCLUSION Compound 1 is a new compound. Compounds 2～7 were obtained from this plant for the first time.