摘要
应用免疫组织化学染色法从1668例尸检肝组织中检出 HBsAg 携带者(简称携带者)78例,检出率4.7%.以8～12岁及20～29岁组携带率较高.97例生前曾检测过血清 HBsAg 的病例中,血清、肝组织 HBsAg 均阳性者16例;血清阳性、肝组织阴性者1例;血清阴性、肝组织阳性者2例.携带者肝组织的病理变化:肝组织正常和非特异反应性炎占84.6%,慢性迁延性肝炎占7.7%,慢性活动性肝炎占2.6%,早期肝硬化占5.1%.本文中12岁以下携带者 HBcAg 阳性率明显高13岁以上携带者(P<0.025).
78 cases of asymptomatic HBsAg carriers were identified among 1668 cases of postmorem liver specimens by using immunohistochemical staining technique. The incidence was 4.7%,with the 8～12years and the 20～29 years groups showing the highest positive rate.In 97 cases tested for serum HBsAg before death,16 cases showed HBsAg positive both in serum and in liver,2 cases were positive in liver but negative in serum,1 case was positive only in serum. Histopathological examination of 78 HBsAg carriers revealed that normal liver and NSRH were present in 84.6% of the carries,CPH was present in 7.7%, CAH was present in 2.6%,the early stage of cirrhosis was present in 5.1%. The results also indicated that the incidence of HBcAg was significantly higher in children carriers than that in those who were elder than twelve (P<0.025).
