摘要
本文通过产后1日龄到30日龄长爪沙鼠肝脏和棕色脂肪组织的线粒体研究揭示,肝线粒体在出生后的呼吸速率、氧化磷酸化作用以及细胞色素氧化酶活力均达到恒定水平。肝线粒体蛋白质量随胎后发育日龄而增加,直至20日龄左右,琥珀酸氧化酶活力在此时也增加到近于恒定,因此肝线粒体产能发育随日龄增长到20日龄左右。这可能是长爪沙鼠体温调节发育的细胞机制之一。从棕色脂肪线粒体的细胞色素氧化酶和琥珀酸氧化酶活力的变化,显示棕色脂肪组织在长爪沙鼠新生幼仔阶段产热中所起的重要作用。
The present paper has showed that the levels of respiratory rate, oxidative phosph-orylation and cytochrome oxidase activity of liver mitochondria at first day after birth in Clawed jird were the same as those of 30 days old. Protein contents of the liver mitochondria increased with developmental stage by about 20 days and mitochondria-produced energy was enhanced with growth by that time. This might be one of the cellular mechanism of thermoregulation in Clawed jird. The changes of cy ochrome oxidase activity and succinate oxidase activity of brown adipose tissue mitochondria displayed that brown adipose tissue played an important role in thermoregulation of neonatal.
出处
《兽类学报》
CAS
CSCD
北大核心
1991年第1期42-47,共6页
Acta Theriologica Sinica
基金
国家自然科学基金资助项目
