清热通下法对急性胆道感染时IL-2和TNF的调节作用

Study on the Regular Function of IL-2,TNF in Acute Bile Duct Infection Using Qingre Tongxia Method of TCM

目的:探讨中医药对急性胆道感染时IL-2、TNF的调节作用。方法:SD大鼠制成急性胆道感染模型,分成A组(模型组)、B组(中药治疗组)、C组(抗生素治疗组)、D组(胆总管结扎组):E组(假手术组)。分别于手术第3、5天取血,做IL-2、TNF的检测。结果:第3天时A组的TNF明显高于其它各组,E组最低,而IL-2在A组最低,E组最高,B、C两组处于A、E两组之间。第5天时TNF、IL-2的总体趋势与第3天相同。结论:中医药在急性胆道感染时对IL-2、TNF有调节作用。

Objective:This study is used to investigate the regular function of IL-2, TNF when the bile duct are acute infection using Chinese herb to cure. Methods:SD rats were made as the model of acute bile duct infection. They are divided into A group(model group), B group(herb therapy group), C group(anti-biotics therapy group), D group(The group with ligation of common bile duct), E group(disguise operation). The blood was taken out to be tested for measuring IL-2,TNF level postoperatively the 3rd day and 5th day. Results:The TNF of A group is more than other groups at 3rd day, the E group is the lowest in 5 group,but the IL-2 of A group is the lowest in 5 groups, The E group is more than other groups, B,C groups are between from A,E groups. 5th day postoperation were as the same results as the 3rd day post operation was obtained. Conclusion:Chinese herb has the regular function for IL-2, TNF on the acute bile duct infection.