钙尔奇D用于妊娠期补钙的临床观察

Clinical experience with caltrate D in pregnancy

目的 观察孕期补钙的效果以及对妊娠的影响。方法 将 4 0 0例孕 2 8周的晚期妇女随机分为补钙组 (2 0 0例 ,服用钙尔奇D 6 0 0片剂 )和对照组 (2 0 0例 ) ,分别于服药前测量血压 ,蛋白尿。观察期间每 2～ 4周查一次血压、宫高、腹围及化验尿蛋白。观察缺钙症状的发生情况。结果 补钙组的临床缺钙症状明显低于对照组 ,且妊高征、胎儿宫内发育迟缓的发生率低于对照组 (P <0 0 1)。结论 妊娠期补充钙尔奇D 6 0 0片剂有益于降低缺钙症状的发生 ,降低妊高征 ,胎儿宫内发育迟缓发生率 ,对母婴均非常有益 。

Objective\ To study the efficacy of Caltrate D supplementation during pregnancy and its impact on pregnancy. Methods\ A total of 400 pregnancy women with 28 gestational weeks were enrolled in this study.There were randomly assigned to 2 groups( n =200) supplemented groups who took Caltrate D1 tablet daily and contrast groups( n =200) who took no other supplementation.Both blood pressure and urinary protein were determined at admission.Blood pressure,uterine height,abdominal circumference and urinary protein were examined every 2～4 weeks. Results\ The incident of clinical calciprive symptom were significantly decreased in supplemented groups than that in contrast groups,pregnancy induced hypertention syndrome(PIH),intranterine fetal growth retardation(IUGR)were distinctly lower than contrast groups( P <0 01). Conclusion\ Caltrate D was benefit to incident of clinical calciprive symptom,PIH and IUGR during pregnancy.It is very benificial for mother and fetus.