阿尔马尔对35例偏头疼的预防作用

Prophylaxis of almarl for 35 cases of migraine

目的 :观察阿尔马尔对偏头痛的预防作用。方法 :采用开放、自身对照试验。 35例偏头痛患者服用阿尔马尔 10mg ,qd ,症状改善不明显时 ,从第 2或第 3周开始 ,改为 10mg ,bid ,疗程 4周。于治疗前后记录偏头痛发作次数 ,评价头痛程度。结果 :患者服药 4周后 ,偏头痛发作次数从 (5 .2± 3.0 )次降至 (3.0± 3.4 )次 (t =5 .6 ,P <0 .0 0 1) ,头痛程度自评分从 (8.1± 0 .7)分降至 (4.9± 2 .8)分 (t=6 .7,P <0 .0 0 1)。总有效率为 6 8.5 %。结论

Objective:To investigate the prophylaxis of almarl for migraine.Methods:35 cases of migraine were treated in an open, self controlled study with daily dose of almarl 10 mg, qd. If no obvious improvement of migraine, 10 mg,bid of almarl was given from second or third week.The attack and severity degree of migraine were recorded and evaluated pre and post treatment. Results:After the treatment of almarl for 4 weeks,the attack of migraine was reduced from (5.2±3.0) to (3.0± 3.4) ( t = 5.6, P <0.001).The severity degree was reduced from (8.1±0.7) to (4.9±2.8) ( t =6.7, P < 0.001).The total effective rate of almarl on migraine was 68.5%.Conclusion:Almarl can reduce both of the attack and severity of migraine.