颈动脉内灌注甘露醇治疗脑出血100例疗效观察

Observation of mannitol infused in carotid on cerebral hemorrhage

目的 :探讨颈动脉内灌注甘露醇治疗脑出血的作用及疗效。方法 :将 2 0 0例脑出血患者随机分为颈动脉内灌注甘露醇加静脉滴注甘露醇治疗组及静脉滴注甘露醇对照组各 10 0例 ,并将两组疗效进行比较。结果 :治疗组 <2 4h和 2 5～48h总有效率分别为 60 .0 5和 5 6.0 % ,对照组 <2 4h和 2 5～ 48h总有效率分别为 5 0 .0 %和 2 0 .0 % ,两组相比存在显著差异( P<0 .0 5 )。结论

Objective: It is to explore the effect of mannitol infused in carotid on cerebral hemorrhage. Methods: Two hundred patients with cerebral hemorrhage were randomly divided into treatment group and control group. One hundred patients in treatment group were given mannitol intracarotid infused and intravenous dripped. One hundred patients in control group were given mannitol intravenous dripped. Results: The total effective rates of the treatment group during 0~24h and 25~48h were 60.0% and 56.0%, and the control group were 50.0% and 20.0%. There was markedly difference between the two groups  (P< 0.05). Conclusion: Mannitol intracarotid infusion on cerebral hemorrhage is safe and effective.