动脉粥样硬化研究新进展:CD40-CD40配体
被引量:1
摘要
CD40 CD40配体广泛存在于动脉粥样硬化病变的各个阶段 ,并且与内皮细胞、平滑肌细胞和单核 /巨噬细胞的功能密切相关 ;阻断CD40 CD40配体的相互作用可以抑制动物动脉粥样硬化的发生与进展。
出处
《国外医学(生理病理科学与临床分册)》
2002年第1期87-89,共3页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
参考文献20
-
1Ross R. Atherosclerosis-an inflammatory disease[J]. N Engl J Med,1999, 340:115 - 126.
-
2Bruemmer D, Riggers U, Holzmeister J, et al. Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions[J]. Am J Cardiol, 2001,87:21-27.
-
3Hakkinen T, Karkola K, Yla-Herttuala S, et al. Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16 (Fc gammaRⅢ) [J].Virchows Arch, 2000, 437:396-405.
-
4Phipps RP. Atherosclerosis: the emerging role of inllammation and the CD40-CD40 ligand system[J] .Proc Natl Acad Sci USA, 2000, 97:6930-6932.
-
5Karpsas M, Hsu YM, Wang JH, et al. 2 A crystal structure of an extracellular fragment of human CD40 ligand[J].Structure, 1995, 3:1031 -1039.
-
6Carbone E, Ruggiero G, Terrazzano G, et al. A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction[J]. J Exp Med, 1997, 185:2053-2060.
-
7van Kooten C, Bancherean J. CD40-CD40 ligand[J].J Leukoc Biol,2000, 67:2-17.
-
8Durie F, Fava R, Foy T, et al. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40[J].Science, 1993, 261:1328 - 1330.
-
9Mach F, Schonbeck U, Sukhova GK, et al. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis[J]. Proc Nail Acad Sci USA, 1997, 94:1931 - 1936.
-
10Kiener PA, Moran-Davis P, Rankin BM, et al. Stimulation of CD40with purified soluble gp39 induces proinflammatory responres in hunan monocytes[J]. J Immunol, 1995, 155:4917-4925.
同被引文献29
-
1韩榜成.OX-LDL的研究进展及在形成动脉粥样硬化中的作用[J].医学综述,1996,2(4):154-157. 被引量:3
-
2Fricker J. A vaccine approach to healthy lipoprotein levels. Mol Med To day, 1999,5(7) :281.
-
3O' Bfien C. Vaccine for atherescleresis. Mol-Med-Today, 1997,3(6): 231.
-
4Charles W. Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherescleresis. Arterioscler Thromb Vasc Biol,2000,9:2106-2112.
-
5Ross R. Atherescler, osis-an inflammatory disease. N Engl J Med, 1999, 340:115-126.
-
6Bruemmer D, Riggers U, Holzmeister J, et al. Expression of CD40 invascular smooth muscle cells and macrophages is associated with early development of human atherescleretic lesions. Am J Cardiol, 2001,87: 21-27.
-
7Hakkinen T, Karkola K, Yla-Herttuala S, et al. Macrophages, smooth muscle cells,endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atheresclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16. Virehows Areh,2000,437:396-405.
-
8Kapsas M , Hsu YM , Wang JH , et al . 2 A crystal structure ! of an extracelluar fragment of human CD40 ligand. Structure, 1995,3:1031-1039.
-
9Carbone E, Ruggiero G, Terrazzano G, et al. A new mechanism of NK xell cytotoxicity activation: the CD40-CD40L ligand interactien. J Exp Med, 1997,185:2053-2060.
-
10Kooten C, Bancherean J. CD40-CD40 ligand. J Leukoc Biol,2000,67:2-17.
-
1陈亚锋,邓长金,胡迎富,代治国,贺爱珍.普伐他汀对高胆固醇血症患者CD40配体的影响[J].微循环学杂志,2009,19(1):31-33. 被引量:3
-
2宋暖,蒋捍东.CD40-CD40配体与肺间质纤维化[J].国外医学(呼吸系统分册),2004,24(3):134-136. 被引量:1
-
3王育珊,李丹.CD40-CD40配体在动脉粥样硬化形成中的作用[J].国外医学(心血管疾病分册),1999,26(4):195-197.
-
4刘丹,张清华.CD40-CD40配体与急性冠脉综合征[J].岭南心血管病杂志,2004,10(4):302-303.
-
5张扬,薛凌.丹酚酸B对动脉粥样硬化CD40-CD40配体信号通路的影响[J].中国医学工程,2012,20(11):6-7. 被引量:8
-
6张峻,陈纪林,顾晴,关婷,陈曦.抗血小板药物抑制动脉粥样硬化进展及机制研究[J].中国循环杂志,2005,20(6):463-467. 被引量:25
-
7王彦永,时军,马晓伟,王铭维.动脉粥样硬化斑块中CD40-CD40配体介导的炎性反应及他汀类药物的抑制作用[J].临床误诊误治,2011,24(1):85-87. 被引量:7
-
8任丽丽,于洪涛.动脉粥样硬化疫苗的研究进展[J].中国生物制品学杂志,2005,18(2):171-173. 被引量:1
-
9薛凌,邱雅慧,张扬,马秀杰,高夏青.CD40-CD40配体系统对兔动脉粥样硬化形成的影响[J].现代预防医学,2012,39(13):3318-3321. 被引量:2
-
10张峻,陈纪林,顾晴,关婷,陈曦.抗血小板药物与阻断CD40信号对动脉粥样硬化的影响[J].中国循环杂志,2008,23(1):57-61. 被引量:14