复方丹参针合参麦针治疗慢性肺源性心脏病临床研究

A Clinical Study on Effects of compound salvia miltiorrhiza injection and “shen mai” injection on the treatment of Chronic Cor Pulmonale

目的 观察复方丹参针合参麦针治疗慢性肺源性心脏病的临床疗效。方法 12 0例患者随机分为治疗组和对照组 ,各 60例。治疗组治以复方丹参针和参麦针 ,对照组患予以抗感染 ,解痉 ,稀释痰液 ,保持呼吸道通畅 ,吸氧 ,强心利尿 ,扩血管等常规治疗措施。治疗前后观察病人气喘、乏力 ,罗音 ,颈静脉充盈 ,心率 ,肝大 ,浮肿等临床症状和体征 ,并进行血气分析、血液流变学参数的动态监测。结果 治疗后治疗组血气分析和血液流变学等参数的改变与治疗前相比具有显著性意义 (P <0 .0 5 ) ,与对照组治疗后相比亦具有显著性意义 (P <0 .0 5 )。治疗组总有效率为 93 .3 3 % ,对照组为 80 % ,两组比较有显著性差异 (P <0 .0 5 )。结论 参麦和复方丹参针治疗肺心病可取得较好的疗效 ,能有效改善心肺功能 ,能改善临床症状和体征 ,而且具有价格低廉 ,无毒副作用等优点 。

Objectives: To observe the effect of compound salvia miltiorrhiza injection and “shen mai” injection on the treatment of Chronic Cor Pulmonale.Methods:120 patients were randomly divided into the treatment group and the control group.Each group involve 60 cases.The treatment group were treated by compound salvia miltiorrhiza injection and “shen mai” injection.The control group were treated by routine therapy such as anti-infection、anti-spasm、dilution of sputum、keeping respiratory tract unobstructed、sucking oxygen、stengthening the function of heart、keeping diuresis、dilatating blood vessel and etc.The clinical symptoms and physical signs such as gasping、inertia、rales、cough、filling of cervical vein、heart rate、cyanosis、hepatomegaly、edema and etc were observed before and after treatment.Blcod gas analysis and hemorheology and SOD were also dynamic monitored.Results: There was a significant difference in blcod gas analysis and hemorheology between pre-treatment and post-treatment in the treatment group(P<0.05).And the significant difference in blcod gas analysis、hemorheology and SOD also existed in the two groups after treatment(P<0.05).The total effective rate in the treatment group was 93.33%,while 80% in the control group.The difference between two groups was significant(P<0.05).Conclusions:Treatment with compound salvia miltiorrhiza injection and “shen mai” injection has good curative effect on chronic cor pulmonale.It can improve cardiorespiratory function and clinical symptoms and physical signs,with the virtue of cheap cost and having no toxic or side effects,deserving application and popularization in clinic.