糖尿病合并冠心病冠状动脉病变特点观察

The investigation of the characterisoics of coronary artery variations in diabetes mellitas (DM) with coronary heart disease

目的 探讨糖尿病合并冠心病冠状动脉病变特点。方法 回顾广东省心血管病研究所 1997～ 1999年冠状动脉造影有阳性发现的病例 ,分为糖尿病组和非糖尿病组(两组均为 6 1例 ) ,分析两组间冠状动脉病变支数及病变类型的差异及不同糖尿病病程患者的冠状动脉病变支数、病变类型的差异。结果 糖尿病组冠状动脉单支病变发生率低(P <0 0 1) ,2支、3支血管病变发生率高 (P <0 0 5 )。A型病变的比例低 (P <0 0 5 ) ,C型病变比例高 (P <0 0 1)。糖尿病不同病程组间的单支、双支、三支血管病变发生率无显著差异 (P >0 0 5 ) ,而糖尿病病程长于 5年组的A型病变较短于 5年组比例低 ,C型病变比例高 (P <0 0 5 )。结论 合并糖尿病的冠心病冠状动脉病变广泛而严重 ,且随着糖尿病的发展而发展。

Objective To investigate the characteristics of coronary artery variations (CAV) in diabetes mellitus (DM) with coronary heart disease (CHD). Methods The cases with postive result in coronary angiography between 1997 to 1999 from Guangdong Provincial Cardiovascular Institute were divided into two groups: diabetes mellitus group and compared group, 61 cases per each group. The difference of the variated of coronary artery branchs and types and different states were analyzed. Results The single branch CAV proportion was lower in DM group than in compared group, ( P <0 01) while the 2 or 3 branchs was reversed ( P <0 05). Type-As rate was low ( P <0 05), while type-C's rate was high ( P <0 01). Different state of DM group of different branchs had indistinct difference ( P >0 05). The CAV proportion had relation with the development of time DM group, type-A's was lower over 5 years, while higher in type-C ( P <0 05).Conclusion It was severe and extensive of CAV in DM with CHD, and was related with the development of DM.