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磷酸钙骨水泥药物缓释载体研究进展 被引量：3

Progress of calcium phosphate cement as drug delivery system
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摘要 本文综述了磷酸钙骨水泥作为药物缓释载体系统在载药前后的特征变化、药物缓释的动力学曲线及其影响因素 。 Calcium phosphate cement(CPC),a novel skeletal defect restorative material,has been widely used in clinical practice.This article has summarized the latest literatures about CPC as a drug delivery system on its realease kinetics and effective factors in order to explain that this system will has favorate application foreground in bone defect restoration in the future.
作者 杨莽 张彩霞 陈德敏
机构地区 上海第二医科大学附属第九人民医院
出处 《国外医学（生物医学工程分册）》 2002年第1期8-11,共4页 Foreign Medical Sciences(Biomedical Engineering Fascicle)
关键词 磷酸钙骨水泥 药物缓释系统 骨缺损 修复 药物缓释载体系统 研究进展 calcuim phosphale cement drug delivery system bone defect restoration
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献20

  • 1Otsuka M,Sawada Y,Matsuda T,et al. Antibiotic delivery system using bioactive bone cement consisting of bis-GMA-TEGDMA resin and bioactive glass ceramics[J]. Biomaterials, 1997,18 (23): 1559-1564.
  • 2Bohner M,Lemaitre J,Landuyt PV,et al. Gentamicinloaded hydraulic calcium phosphate bone cement as antibiotic delivery system[J]. Journal of Pharmaceutical Sciences, 1995,84 (5): 565-572.
  • 3Otsuka M,matuda Y,Suwa Y,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 5. Drug release behavior from a heterogeneous drug-loaded cement containing an anticancer drug[J]. Journal of pharmaceutical Sciences, 1994,83(11) :1565-1568.
  • 4Otsuka M,matsuda Y,Suwa Y,et al. Anovel skeletal drug delivery system using self-setting calcium phosphate cement. 4. Effects of the mixing colution volume on the drug-release rate of heterogeneous aspirin-loaded cement [J]. Journal of Pharmaceutical Sciences,1994,83(2): 259-263.
  • 5Yu D,Wong J,Matsuda Y,et al. Self-setting hydroxyapatite cement: A novel skeletal drug-delivery system for antibiotics[J]. Journal of Pharmaceutical Sciences,1992,81 (6): 529-561.
  • 6Otsuka M,Matsuda Y,Suwa Y,et al. Anovel skeletal drug delivery system using self-setting calcium phosphate cement. 2. Physicochemical properties and drug release rate of the cement-containing indomethacin[J]. Journal of Pharmaceutical Sciences, 1994,83 ( 5 ):611-615.
  • 7Otsuka M,Matsuda Y,Suwa Y,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 3. Physicochemical properties and drug release rate of bovine insulin and bovine albumin[J].Journal of Pharmaceutical Sciences, 1994,83 (2): 255-258.
  • 8Otsuka M,Nakahigashi Y,Matsuda Y,et al. A novel skeletal drug deliery system using self-setting calcium phosphate cement. 7. Effect of biological factors on indomethacin release from the cement loaded on bovine bone[J]. Journal of Pharmaceutical Sciences, 1994,83(11): 1569-1573.
  • 9Otsuka M,Matsuda Y,Fox JL,et al. A novel skeletal drug delivery system using self-setting calcium phosphate cement. 9. Effects of the mixing solution volume on anticancer drug release from homogeneous drugloaded cement[J] ,Journal of Pharmaceutical Sciences,1995,84(6) :733-736.
  • 10Takechi M,Miyamoto Y,Ishikawa K,et al. Effects of added antibiotics on the basic properties of antiwashout-type fast-setting cacium phosphate cement[J]. J Biomed Mater Res, 1998,39(2) :308-316.

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国外医学（生物医学工程分册）
2002年 第1期

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