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降纤酶治疗急性脑梗塞的临床研究

Clinical Study on Defibrase Treating Acute Cerebral Infarction
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摘要 目的 观察降纤酶治疗急性脑梗塞的临床疗效。方法  81例患者随机分治疗组 46例和对照组 35例。治疗组应用降纤酶每次 5BU ,每日 1次 ,静脉滴注 ,连用 5天。对照组应用低分子右旋糖酐 +复方丹参每日 1次 ,静脉滴注 ,连用14天。结果用 χ2 检验进行统计学分析。结果 治疗组疗效明显高于对照组 (P <0 .0 1) ,发病 2 4小时内用药的疗效显著高于 2 4小时后用药组 (P <0 .0 1)。结论 早期应用降纤酶治疗急性脑梗塞有明显疗效。 Objeetive To observe the therapeutic effect of defibrase on acute cerebral infarction.Method 81 cases of acute cerebral infarction were randomly divided into two groups.The treatment group(n=46) was treated with defibrase(5BU/d),iv for 5d.The control group(n=35) was treated with dextran 40 and radix salvia miltiorr hizae comosita,iv for 14d.The results were analyzed statistically with χ 2 test.Results The therapeutic effect in the treatment group was significantly better than that in the control group( P <0.01).The therapeutic effect in patients treated within 24h was significantly better than that in those treated over 24h( P <0.05).Conclusion The defibrase given in the early stage is obviouslyeffective in treating actue cerebral infarction.
出处 《现代诊断与治疗》 CAS 2002年第2期85-87,共3页 Modern Diagnosis and Treatment
关键词 降纤酶 急性脑梗塞 药物治疗 临床研究 Defibrase Acute cerebral infarction
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