94例老年患者药物不良反应分析

Adverse drug reactions in 94 elderly patients

目的:分析94例老年患者ADR的分布及相关因素。方法:从我院历年的患者ADR报告表中,选出60岁以上的老年患者ADR报告表,逐项统计整理。结果:①老年患者ADR占39.5％,男>女;原患疾病以心脑血管疾病及感染性疾病居多。②94例老年患者ADR的临床表现以皮肤反应和神经系统反应为主,列居第一、二位。③诱发ADR的药物主要是抗菌药物和治疗心脑血管病的药物。结论:老年人药物治疗中,合并用药及原患疾病状况等情况与ADR的发生关系密切。

Objective: To analyze adverse drug reactions and its related factors in 94 elderly patients. Method: ADR reporting forms over years of our hospital were collected and reviewed. Results: 1 .Patients with ADR over 60 years old accounted for 39.5% of all ADR forms, occuring more in male than in female. 2.Clinical manifestations of dermoreaction and nervous system reaction were demonstrated, ranking the first and second respectively on the ADR order list. 3. Most drugs of inducing ADR were for the treatment of cardiac cerebral - vascular diseases and infectious diseases. Conclusion: Occurrence of ADR in the elderly is in the close relation with their original diseases and the combined use of drugs.