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膦甲酸的肾毒性

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摘要 膦甲酸是一种广谱抗病毒药物,可有效治疗巨细胞病毒(CMV)、单纯疱疹病毒感染和人类免疫缺陷病毒感染。研究表明,应用膦甲酸治疗期间可发生电解质紊乱、酸中毒、贫血、发热、呕吐等副作用,膦甲酸的肾毒性主要有以下表现:引起急性肾功能衰竭(病理改变表现为肾小球新月体形成、肾小管性间质性肾炎)、肾小管性酸中毒、肾小管性尿崩症等。
作者 卢文宁 黄宇
出处 《药物不良反应杂志》 2002年第1期26-28,共3页 Adverse Drug Reactions Journal
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参考文献9

  • 1Walmsleys, TsengA. Comparative tolerability of therapies for cytomegalovirus retinitis. Drug Safety, 1999, 21 (3):203.
  • 2Chatelain E , Deminiere C, Lacut JY, et al. Severe renal failure and polyneuritis induced by foscarnet. Nephrology Dialysis Transplantation, 1998, 13: 2368.
  • 3Zaman MM, Burney S, Landman D, et al. Rapid development of renal insufficiency with the simultaneous administration of amphotericin B and foscarnet. Clinical Infectious Diseases, 1996, 22 (5): 378.
  • 4Nyberg G, Blohme I, Persson H, et al. Foscarnet - induced tubulointerstitial nephritis in renal transplant patients. Transplantation Proceedings, 1990, 22: 241.
  • 5Trolliet P, Dijoud F, Gotte L, et al. Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet. Am J Nephrol ,1995, 15: 256-259.
  • 6Navarro JF, Quereda C, Moreno A, et al. Renal tubular acidosis following treatment with foscarnet. AIDS, 1995,9: 1389- 1390.
  • 7Tarese Jr RV, Schambelan M, Hollander H, et al.Nephrogenic diabetes insipidus associated with foscamet treatment of cytomegalovirus retinitis. Annals of Internal Medicine, 1990, 112: 955-956.
  • 8Deray G, Katlama C, Dohin E, et al. Prevention of foscarnet nephrotoxicity. Annals of Internal Medicine, 1990,113: 332.
  • 9Deray G, Martinez F, Katlama C, et al. Foscarnet nephrotoxicity: mechanism, incidence and prevention. Am J Nephrol, 1989, 9: 316.

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