期刊文献+

紫外光诱导的细胞凋亡与神经酰胺的相关性 被引量:1

下载PDF
导出
摘要 神经酰胺(ceramide)是一种脂质信号分子,它调节细胞分化、增殖和凋亡。神经酰胺不仅参与TNF、Fas等细胞因子对细胞的多样性刺激,而且介导紫外光等环境应激因子所诱导的细胞凋亡。本文介绍了神经酰胺代谢、神经酰胺介导紫外光诱导的凋亡信号途径及其调控机制。
出处 《中国临床康复》 CSCD 2002年第6期860-861,共2页 Chinese Journal of Clinical Rehabilitation
  • 相关文献

参考文献10

  • 1ARAGANE Y,KULMS D,METZE D,et al. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO 1) independently of its ligand CD95L[J]. J Cell Biol,1998,140(1):171-182.
  • 2KOLESNICK RN,KRONKE. Regulation of ceramide production and apoptosis[J].Annu Rev Physiol,1998,60:643-665.
  • 3VERHEIJ M,BOSER,LIN XH,et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress induced apoptosis[J].Nature,1996,380:75-79.
  • 4KIDD VJ. Proteolytic activities that mediate apoptosis[J].Annu Rev Physiol,1998,60:533-573.
  • 5ARORA AS,JONES BJ,PATELTC,et al. Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat[J].Hepatology,1997,25:958-963.
  • 6KROEMER G,DALLAPORTA B,RESCHE RIGON M. The mitochondrial death/life regulator in apoptosis and necrosis[J].Annu Rev Physiol,1998,60:619-642.
  • 7CUVILLIER O,PIRIANOV G,KLEUSER B,et al. Suppression of ceramide mediated programmed cell death by sphingosine-1-phosphate[J].Nature,1996,381:800-803.
  • 8KROEMER G,ZZMZANI N,SUSIN SA. Mitochondrial control of apoptosis[J].Immunol Today,1997,18:44-51.
  • 9YANG J,LIU X,BHALLA K,et al. Prevention of apoptosis by Bcl 2 release of cytochrome c from mitochondria blocked[J]. Science,1997,275:1129-1132.
  • 100ADAMS JM,CORY S.The Bcl 2 protein family:arbiters of cell survival[J].Science,1998,281:1322-1326.

同被引文献12

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部