玄麦咽康含片的解热与体内外抑菌实验研究

Experimental Study on Antipyretic and in Vitro and in Vivo Bacteriostatic Effects of Xuanmia-Yankang Buccal Tablets(XBT)

目的 :研究玄麦咽康含片的解热、体内外抑菌作用。方法 :采用大鼠干酵母致热模型及常规的体内、外抑菌实验法 ,观察玄麦咽康含片的解热作用及体内外抑菌作用。结果 :玄麦咽康含片能显著抑制干酵母所致的大鼠发热 ;对甲型溶血性链球菌、乙型溶血性链球菌、肺炎双球菌、金黄色葡萄球菌均有明显的体外抑制作用 ,对乙型溶血性链球菌感染的小鼠有一定的保护作用。结论 :玄麦咽康含片具有解热和体内。

OBJECTIVE:To study the antipyretic,in vitro and in vivo bacteriostatic effects of XBT METHODS:Experimen_ts were carried out on a rat model of using dry-yeast as pyretogenic agent and by conventional in vitro and in vivo antimicrobial tests,and the antipyretic and bacteriostatic effects of XBT were observed RESULTS:XBT can significantly inhibit the pyretogenesis induced by dry-yeast in rats;The result of antimicrobial experiment showed that XBT could significantly inhibit α-hemolytic streptococcus,β-hemolytic streptococcus,streptococcus pneumaniae,and staphylococcus aureus in vitro It showed protective effects on infection with β-hemolytic streptococcus CONCLUSION:XBT have antipyretic and bacteriostatic effects