AEV-NH937引起禽脑脊髓炎的病理学观察

Pathological Observations of Avian Encephalomyelitis Caused by AEV-NH937

用禽脑脊髓炎病毒 NH93 7毒株脑内接种 1日龄 SPF雏鸡 ,分别在攻毒后 3 ,5,1 0 ,1 4 ,2 0 ,2 5和 3 0 d分别宰杀对照组两只和攻毒组 4只 ,取大脑和小脑、固定、HE染色。结果临床发病在第 6天出现 ,第 9天普遍发病并开始死亡 ,到第 1 4天死亡停止。在第 3天时 ,软脑膜充血出血、神经元出现少量变性坏死 ,第 1 0天和 1 4天损伤性变化最重 。

day old SPF chickens were injected with AEV NH 937 via intracerebral inoculation and killed at 3,5,10,14,20,25,30 days (2 of control and 4 of injected) after injection, respectively. Their cerebrum and cerebellum were collected, fixed and stained with HE . The result showed :The disease occurred in the 6th day , all of them callght disease and gradually died from 9th day to 14th day after jection . In the 3rd day, pia mater was in hyperemia and hemorrhage, neurocyte began necrosis; in the 10th～14th day the injury change was the most serious. Then, perivascular cuffing and glia proliferating became the main changes.