金属结合蛋白基因及其在清除重金属污染中的应用

Genes of Metal-binding Proteins and Their Application in Bioremediation of Heavy Metals

一些微生物和植物由于对毒性金属具有独特的抗性机制 ,使得利用它们来清除日益严重的环境污染已发展成为一种十分有效的技术———生物修复。研究表明 ,不同的金属结合蛋白 (如MT和PC) ,在生物忍耐和降解过量重金属毒性机制中起重要作用。愈来愈多的MT和PC基因被克隆 ,并已成功地应用于生物遗传转化 ,这些转基因生物在清除重金属污染方面已显示出潜在的应用价值。

Heavy metal pollution has become a global environmental hazard.The use of microorganisms and plants for the decontamination of heavy metals is recognized as a low lost and high efficiency method for cleaning up metal contamination.It shows that various metal-binding proteins such as metallothioneins (MTs) or phytochelatines (PCs) play an important role in defense systems and detoxification to heavy metals in organisms.Many genes of MTs and PCs have been cloned and utilized successfully in genetically modified bacteria and plants for increasing remediation capacity.These transgenic organisms have been displayed a great potential in bioremediation and phytoremediation of heavy metals.