采用询检法确定血吸虫病化疗对象的研究

Determining Schistosomiasis Chemotherapy Object by Inquiry Method

目的为提高血吸虫病高度流行区人群化疗依从性 ,比较询检法化疗与全民化疗控制血吸虫病的效果、费用。方法选择湖沼垸外型的三浃、芦洲两个高度流行村 ,分别采用询检法化疗和全民化疗 ,纵向比较两种化疗方法的效果及费用等。结果通过两年实施 ,询检法化疗人群覆盖率及受治率均明显高于全民化疗 (P<0 .0 0 1 ) ,控制血吸虫病效果两方法差异无显著性 (P>0 .0 5 )。询检法每 1 0 0人化疗费用较全民化疗费用低 4.2 0元。结论询检法化疗控制血吸虫病的效果与全民化疗差异无显著性 ,但具有人群覆盖率高、费用低等特点 。

Objective To enhance the chemotherapy compliance of masses in hyper endemic areas and to make comparison of the effectiveness and benefit between mass chemotherapy method and selective chemotherapy after inquiry method. Methods Two years ′ longitudinal comparison on human infection rate, chemotherapy coverage rate, actural treatment rate and cost benefit analysis were made in two hyper endemic demonstration villages carried out above mentioned different chemotherapy methods. Results Both chemotherapy coverage rate and actual treatment rate were remarkablly higher in village applied inquiry method than in village with mass chemotherapy method ( P <0.001) while the human infeciton rate revealed no differences ( P >0.05) between the two villages. The chemotherapy expenditure per 100 persons in inquiry method village was 4.20 yuan lower than that in mass chemotherapy village. Conclusion Selective chemotherapy after inquiry method was better than mass chemotherapy method.