Duane眼球后退综合征合并先天性鳄鱼泪25例临床分析

A clinical analysis of 25 cases with Duane′s retraction syndrome combined with congenital crocodile tears

目的 探讨Duane眼球后退综合征 (Duane′sretractionsyndrome ,DRS)合并先天性鳄鱼泪的临床表现。方法 回顾性总结和分析 2 5例DRS合并先天性鳄鱼泪患者的临床特征 ,包括性别、初诊年龄、眼别、DRS类型、异常流泪特征和其伴随的眼部和非眼部异常表现。结果 男性患者 8例 ,女性患者 17例 ,男女性别比约为 1∶2 ;双眼受累患者 15例 ,单眼受累患者 10例 ;双眼DRS患者出现单眼鳄鱼泪者 3例 ,单眼DRS患者出现双眼鳄鱼泪者 1例 ,其余 2 1例患者均为单眼DRS患者鳄鱼泪症状表现在同侧 ,双眼DRS患者鳄鱼泪症状表现在双侧。结论 DRS合并先天性鳄鱼泪患者在临床虽较为少见 ,但充分重视和掌握其临床特征 。

Objective To analyze the clinical manifestations of Duane′s retraction syndrome (DRS) combined with congenital crocodile tears or gustatory lacrimal reflex. Methods Twenty five cases of DRS associated with congenital crocodile tears were retrospectively summarized The clinical features, including sex, age at first visit, chief complaints, laterality, types of DRS, features of abnormal lacrimation and its associated ocular and non ocular anomalies were analyzed Results There were 8 males and 17 females with a male to female ratio of 1∶2 Fifteen cases had binocular involvement and the remaining 10 cases were monocular involvement In general, the association of the abnormal lacrimation and eye movement disorder in unilateral cases was ipsilateral, while in bilateral cases the abnormal lacrimation and the movement disorder were also bilateral except3 cases of bilateral DRS with monocular crocodile tears and one case of unilateral DRS with binocular crocodile tears Conclusions Clinically, cases with Duane′s syndrome combined with crocodile tears are relatively few. That sufficiently pay attention to and master its clinical characteristics is the basis for its correct diagnosis.