中药白及中一新的联苄化合物

A NEW BIBENZYL DERIVATIVE FROM BLETILLA STRIATA

目的 研究中药白及Bletillastriata (Thunb .)Reichb .f.根茎的化学成分。方法 利用硅胶柱及SephadexLH 2 0等色谱技术进行分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果 得到 3个化合物 ,分别鉴定为 5 羟基 4 (对羟基苄基 ) 3′ ,3 二甲氧基联苄 (I) ,五味子醇甲 (II) ,4,4′ 二甲氧基 2 ,2′,7,7′ 四羟基 1,1′ 联菲 (III)。结论 I为新化合物 ,II为从该植物中首次分得。

AIM To study the chemical constituents of Bletilla striata . METHODS Various column chromatographies with silica gel and Sephadex LH-20 were employed for the isolation and purification. The structures of the compounds were elucidated on the basis of spectral analyses and chemical methods. RESULTS Three compounds were isolated from the roots of Bletilla striata (Thunb.) Reichb. f. and identified as 5-hydroxy-4-( p -hydroxybenzyl)-3′,3-dimethoxybibenzyl (I), schizandrin (II), 4,4′-dimethoxy-(1,1′-biphenanthrene)-2,2′,7,7′-tetrol (III). CONCLUSION Compound I is a new bibenzyl derivative and II was isolated from this plant for the first time.