期刊文献+

在糖尿病患者使用贝特类和他汀类预防动脉粥样硬化 被引量:1

下载PDF
导出
摘要 动脉粥样硬化性心血管病是糖尿病最常见的并发症,最近美国的治疗指南强调了在糖尿病患者治疗脂质代谢异常的重要性,以降低这种并发症的危险性。如果生活方式的改善不足以奏效,则需要加用药物治疗。两类最常用的纠正脂蛋白异常的药物是他汀类和贝特类药物。每一类药物起着不同的作用,其使用取决于所存在的脂质异常的特征。因此,不能将它们的应用考虑为“两者任一/或”的情况,这篇综述将讨论每一类药物的应用。此外,这些药物带来的疗效不能完全用对脂蛋白异常的纠正来解释,因此,也将对它们的非脂质作用即抗动脉粥样硬化的调脂以外作用进行回顾。
出处 《世界医学杂志》 2002年第6期9-13,共5页 International Journal of Medicine
  • 引文网络
  • 相关文献

参考文献46

  • 1Bierman EL. George Lyman Duff Memorial Lecture. Atberogenesis in diabetes. Artericscler Thromb 1992; 12: 647-656.
  • 2UK Prospective Diabetes Study 27. Plasma lipids and lipoproteins at diagnosis of NIDDM by age and sex. Diabetes Care 1997; 20: 1683-1687.
  • 3Stamler J, Vaccaro O, Neaton JD, Wentwortb D. Diabetes. other risk factors, and 12-yr cardiovascular mortality for men screende in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993; 16: 424-444.
  • 4Mykkanen L. Kuusisto J, Haffner SM. etal. LDL size and risk of ecronary heart disease in elderly men and women. Arterioscler Thromb Vasc Biol 1999; 19 2742-2748.
  • 5Lehto S. Ronnemaa T. Haffner SM, etal. Dyslipidemia and byperglycemia predict coronary beart disease events in middle-aged patients with NIDDM. Diabetes 1997; 46:1354-1359.
  • 6Expert Panel on Detection Evaluation, and Treatment of High Blood Cbolesterol in Adults. Exccutive suromary of the third rcport of the National Cbolesterol Education Program (NCEP) Expert Panel on Detection, Evaluation. and Treatment of High Blood Cholesterul in Adults (Adult Treatment Panel Ⅲ)[see comments]. JAMA 2001;285:2486-2497.
  • 7Haffner SM, Lehto S,Ronnemaa T,etal. Mortality From coronary heart discase in subjects with type 2 diabetes and in nondisbetic subjects with and witbout prior myocardial in farction [see comments]. N Engl J Med 1998.339: 229-234.
  • 8Maron DJ.Fazjo S,Linton MF. Current perspectives on stations. Circulation 2000; 101: 207-213.
  • 9Guijarro C, Blanco-Colio LM, Ortego M, etal. 3-Hydroxy-3-metbylglutaryl coenzyme a reductase and isoprenylation inbibitors induce apoptiosis of vascular smooth muscle cells in culture Circ Res 1998; 83 490-500.
  • 10Feuton JWll, Shen GX, Minneay FL,etal. Statin drugs and dietary isoptenoids as antithrombotic agents. Hematol Oncol Clin N Am 2000;14:483-490.

同被引文献2

引证文献1

二级引证文献2

;
使用帮助 返回顶部