功能性子宫出血内膜血管CD34和LN的变化

Changes of CD34 and LN in Endometrial Vessels of Dysfunctional Uterine Bleeding

为探讨功能性子宫出血的原因 ,采用组织学和免疫组织化学方法 ,对功能性子宫出血的内膜与正常内膜进行了组织学和CD34及层粘连蛋白 (LN)的比较观察。组织学观察显示 :功能性子宫出血的内膜发育呈不同步状态 ,并有不同程度的局灶性出血 ,出血部位的血管多呈断裂像。经图像分析仪测定显示 :出血内膜组织的血管内皮细胞CD34和血管基膜的LN阳性反应明显减弱。提示功能性子宫出血与血管中CD34和LN的减少有关。

To investigate the causes resulting in dysfunctional uterine bleeding, the endometrial vessels of normal and dysfunctional uterine bleeding were observed morphologically, and CD34 and LN were examined by immunohistochemistry. Results showed that there were lots of breaks in endometrial vessels of bleeding and the quantity of CD34 and LN decreased obviously. It can be concluded the decreases of CD34 and LN are closely related with the dysfunctional uterine bleeding.