摘要
手术病人术后2天和7天外周血单个核细胞(PBMC)的T淋巴细胞转化及白介素2(IL2)的生成均明显降低。50~250μg/ml的黄芪多糖(APS)、0.1~100μg/ml的人参茎叶皂甙(GSL)在体外对术后7天PBMC的T淋巴细胞转化及IL2的生成均具有不同程度的升高作用,表明APS、GSL对手术病人PBMC具有直接的刺激活性。
T lymphocyte transformation and interleukin 2(IL 2) production of peripheral blood mononuclear cell(PBMC) in operated patients were decreased following 2 and 7 days post operation. Astragalus polysaccharides (APS) at the concentration of 50~250μg/ml,Ginsenosides of stem and leaf (GSL) at the concentration of 0.1~100μg/ml could in vitro elevate T lymphocyte transformation and IL 2 production of PBMC after 7 days post operation. It is suggested that APS, GSL may stimulate PBMC of operated patients directly.
出处
《中药药理与临床》
CAS
CSCD
1997年第4期13-15,共3页
Pharmacology and Clinics of Chinese Materia Medica
关键词
黄芪多糖
人参茎叶皂甙
外科手术
细胞免疫
免疫功能
Astragalus polysaccharides,Ginsenosides of stem and leaf,operation,cellular immunity