桂枝汤对胃肠运动双向调节作用的研究Ⅱ.对胃动素、胃泌素含量的影响

Experimental Study of Guizhi Tang (Cinnamon Twig Decoction) on Dual direction Regulation of Gastrointestinal Motility Ⅱ.Effect on Gastrin and Motilin

桂枝汤可降低新斯的明性胃肠功能亢进大鼠的下丘脑、血液、胃窦、十二指肠和空肠胃泌素、胃动素含量的升高；也可使阿托品性胃肠功能受抑大鼠的胃泌素、胃动素含量升高，并使之趋向正常；而对正常大鼠却无明显的影响，提示本方对胃肠运动机能的双向调节是通过调节中枢下丘脑、血液、胃肠局部组织中的胃泌素。

Guizhi Tang(Cinnamon Twig Decoction,GT) might cut down the rise of gastrin and motilin content in plasma,hypothalamus,gastric antrum,duodenum and jejunum induced by neostigmine.Atropine lowered the two kinds of gastrointestinal hormone in these tissues,and GT might antagonized the decrease of the hormone contents.In addition,GT didn't influence gastrin and motilin contents in normal rats.Results indicate that GT may rugulate the function of gastrointestinal motility in dual direction by means of influencing on gastrointestinal hormone contents in hypothalamus,gastric antrum,duodenum and jejunum.