摘要
消癃通闭浸出液与犬大脑皮层粗制膜及IBE12 5作用测定其对IBE12 5与犬大脑皮层α1 AR结合的抑制作用 ,结果消癃通闭对IBE12 5犬大脑皮层的结合呈竞争性拮抗作用 ,IC50 为 3 4 0± 6 0 g/L ,Hill系数为 0 70± 0 0 6,佐证本方具有α1 AR拮抗作用。
The inhibition of XLTB (Xiaolong Tongbi) on the combination between IBE 125 adn α 1-adrenalin receptor (α 1-AR) in canine cerebral cortex was studied. Results indicated that the competitive antagonism of XLTB on combination on IBE 125 and α 1-AR in canine cerebral cortex was showed and IC 50 was 34.0±6.0g/L, hill coefficient was 0.70±0.06.
出处
《中药药理与临床》
CAS
CSCD
2000年第3期31-32,共2页
Pharmacology and Clinics of Chinese Materia Medica
基金
国家自然科学基金资助课题! (392 70 856)