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原发性肝静脉梗阻的介入治疗

Clinical Application of PTA in the Treatment of Primary Hepatic Venous Obstruction
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摘要 Purpose To evaluate the efficacy of percutaneous transluminal angioplasty (PTA) in treating the patients with primary hepatic venous obstruction. Methods Six patients with hepatic venous obstruction were enrolled into this study.3 patients were treated with anterograde transhepatic angioplasty,the other 3 patients were treated with retrograde angioplasty via inferior vena cava(IVC).The diameter of hepatic vein and hepatic venous pressure gradient (HVPG) were recorded before and after therapy.Data were analyzed with Paired Samples t Test. Results All PTA procedures were performed successfully.After therapy the diameter of hepatic vein was increased from (0.90±1.03)mm to (5.67±0.34)mm( P <0.001) and the HVPG was declined from (4.15±0.53)kPa [(31.23±4.04)mmHg] to (1.21±0.10)kPa [(9.13± 0.76 )mmHg] ( P <0.001).Difference showed statistical significance.The patients’clinical signs and symptoms were improved obviously.There was no serious procedure related complication except one patient experienced intraperitioneal bleeding. Conclusions PTA is a safe and effective treatment for patients with primary hepatic venous obstruction. Purpose: To evaluate the efficacy of percutaneous transluminal angioplasty (PTA) in treating the patients with primary hepatic venous obstruction. Methods: Six patients with hepatic venous obstruction were enrolled into this study. 3 patients were treated with anterograde transhepatic angioplasty, the other 3 patients were treated with retrograde angioplasty via inferior vena cava (IVC). The diameter of hepatic vein and hepatic venous pressure gradient (HVPG) were recorded before and after therapy. Data were analyzed with Paired-Samples t Test. Results: All PTA procedures were performed successfully. After therapy the diameter of hepatic vein was increased from (0.90 ± 1.03) mm to (5. 67 ± 0.34) mm (P < 0.001) and the HVPG was declined from (4.15 ± 0.53)kPa [(31.23 ± 4.04) mmHg] to (1.21 ± 0.10) kPa [(9.13 ± 0.76) mmHg] (P<0. 001). Difference showed statistical significance. The patients' clinical signs and symptoms were improved obviously. There was no serious procedure-related complication except one patient experienced intraperitioneal bleeding. Conclusions: PTA is a safe and effective treatment for patients with primary hepatic venous obstruction.
出处 《复旦学报(医学版)》 EI CAS CSCD 北大核心 2002年第2期147-149,共3页 Fudan University Journal of Medical Sciences
关键词 原发性肝静脉梗阻 球囊扩张 介入治疗 PTA Patient monitoring Statistical methods
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参考文献8

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