409例胃息肉患者的临床与病理特点解析

Analysis of Clinical and Pathological Characteristics of 409 Patients with Gastric Polyps

目的分析胃息肉患者的临床及病理特点,对胃息肉防治提供一定的临床依据。方法将2015年9月1日~2017年10月31日在武汉市第三医院住院,发现胃息肉并行内镜下治疗、病检明确胃息肉的409例患者纳入观察。回顾分析患者的一般资料,临床及病理特征。结果各类息肉在性别及不同年龄段的构成中差异无统计学意义(P>0.05)。增生性息肉、胃底腺息肉、炎性息肉是常见的病理类型,分别为148例、135例、119例,占比为36.19%、29.1%、33%。胃息肉发生部位依次为胃体、胃底、胃窦,分别为38.64%、37.65%、22.24%。Hp阳性259例,感染率63.33%,其中增生性息肉、炎性息肉、胃底腺息肉、腺瘤性息肉的Hp感染率分别为70.27%(104例)、78.99%(94例)、40.74%(55例)、85.71%(6例)。不同病理类型息肉的发生部位及Hp感染因素差异有统计学意义(P<0.05)。结论分析胃息肉临床、病理特点有助于内镜下息肉的判断,减少漏(误)诊;胃息肉与Hp感染关系密切,临床治疗胃息肉的同时,应重视根除Hp感染,减少术后复发、癌变。

Objective To analyze clinical and pathological characteristics of gastric polyps in order to provide clinical evidence for the prevention and treatment of polys.Methods 409patients who were diagnosed as gastric pol- yps by pathological examination from Sep.1,2015to Oct.31,2017in Wuhan Third Hospital were included in this study.Clinical and pathological data were retrospectively analyzed and summarized.Results There was no significant difference on the proportion of polyps in gender and age (P >0.05).Hyperplastic polyp (148cases,36.19%),fundic gland polyp (135cases,29.1%)and inflammatory polyp (119cases,33%)were common pathological types.The com-mon location of gastric polyps were gastric body(38.64%),fundus (37.65%)and antrum (22.24%).Patients with Hp positive were 259cases with infection rate of 63.33%.Hp infection rates of hyperplastic polyp,inflammatory polyp,gastric fundic polyp and adenomatous polyp were 70.27%(104cases),78.99%(94cases),40.74%(55cases) and 85.71%(6cases).There were significant differences on location and Hp infection between different pathological types of polyps (P <0.05).Conclusion The analysis of clinical and pathological features of gastric polyps can help to diagnose polyps by endoscope and reduce missed diagnosis and misdiagnosis.Gastric polyp is closely associated with Hp infection.The eradication of Hp infection should be emphasized in the treatment of gastric polyps in order to reduce recurrence and malignant transformation.