不同干燥方法对远志筒及根中主要化学成分的影响

Effects of different drying methods on active constituents of root bark and root of Polygala tenuifolia

目的考察晒干、阴干、热风干燥(40、50、60、70℃)、微波干燥和冷冻干燥5种干燥方法对远志筒及根中主要化学成分的影响。方法运用HPLC法测定不同干燥方法对远志筒及根中远志酮III、3,6′-二芥子酰基蔗糖、远志酸、远志皂苷元、细叶远志皂苷的组成和含量变化;采用单因素方差分析和TOPSIS法对数据进行综合分析。结果远志筒和根的干燥方法优选顺序存在差异,远志筒不同干燥方法对有效成分影响的优劣排序为微波干燥>60℃热风干燥>50℃热风干燥>70℃热风干燥>冷冻干燥>40℃热风干燥>阴干>晒干;远志根中,不同干燥方法的排序为微波干燥>60℃热风干燥>阴干>晒干>50℃热风干燥>40℃热风干燥>70℃热风干燥>冷冻干燥。结论结合生产实践,微波干燥和60℃热风干燥是远志筒和根较适宜的干燥方法,可为远志不同规格药材产地干燥方式的确定提供依据。

Objective To investigate the effects of different drying methods on composition and content of five active constituents in root bark and root of Polgala tenuifoliaroot.Methods The contents ofpolygalaxanthone Ⅲ,3,6'-disinapoyl sucrose,polygalacic acid, senegenin,and tenuifolin in root bark and root from different drying samples were determined by HPLC.Then the data analysis was performedby ANOVA and TOPSIS methods.Results There is a difference in the order of drying methods for bark and root of P. tenuifoliaroot.For P.tenuifoliaroot root bark,the order of different drying methods was microwave drying >60℃ hot-air drying > 50℃ hot-air drying >70℃ hot-air drying >freeze-drying >40℃ hot-air drying >shade drying >sun drying;For P.tenuifolia root,the different drying methods were sorted by microwave drying >60℃ hot-air drying >shade drying >sun drying >50℃ hot-air drying >40℃ hot-air drying >70℃ hot-air drying >freeze-drying.Conclusion Combined with the production practice, this study suggests that microwave drying and hot-air drying at 60℃ are suitable drying methods for P.tenuifoliaroot bark and root, providing a basis for the determination of drying methods for the origin processing of P.tenuifolia.