冠心病痰浊证与脂蛋白代谢的研究进展

Review of coronary artery heart disease with syndrome of phlegm turbidity and lipoprotein metabolism

脂蛋白作为血液中的脂类载体,其代谢异常是冠心病的主要风险因素之一。而从中医学角度则认为冠心病的发生和发展与痰浊形成密切相关。目前许多研究认为冠心病痰浊证与脂蛋白代谢之间存在关联。文章对冠心病痰浊证与LDL-C、HDL-C、载脂蛋白、LP(a)相关的研究进行综述,建议在冠心病的研究中,应加强对痰浊证的深入研究、寻找痰浊证客观指标的脂蛋白、参考国外最新的脂蛋白机制成果、并期待权威学术机构建立冠心病痰浊证的临床研究标准。

One of the major risk factors of coronary artery heart disease is abnormal metabolism of lipoprotein which is the carrier of lipid in blood.However,the occurrence and development of coronary artery heart disease is closely related to phlegm turbidity in TCM.A number of studies suggest that there is a correlation between the syndrome of phlegm turbidity and lipoprotein metabolism in coronary artery heart disease.This article reviews the researches on the correlation between syndrome of phlegm turbidity of coronary artery heart disease and LDL-C,HDL-C,lipophorin and LP (a).In studies of coronary artery heart disease,it suggests that make the further study of syndrome of phlegm turbidity,try to find the lipoprotein represent of syndrome of phlegm turbidity,cite the latest achievements of lipoprotein mechanism in the world and look forward to the relative standard of clinical study by authoritative academic institutions.