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甲状腺功能正常孕早期妇女TPO抗体阳性对妊娠结局的影响 被引量:2

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摘要 目的:研究甲状腺功能正常孕早期妇女甲状腺过氧化物酶(TPO)抗体阳性对妊娠结局的影响。方法:选取2016年6月至2017年6月期间在重庆市荣昌区妇幼保健院进行孕检的120例孕早期妇女作为研究对象,按照其TPO抗体的性质将其分成阳性组和阴性组,阳性组40例,阴性组80例。观察并比较所有孕妇妊娠过程中的甲状腺功能变化情况、产科并发症的发生率以及新生儿出生后的临床特征。结果:两组孕妇的甲状腺功能紊乱发生情况以及产科并发症的发生率比较,组间比较,差异具有统计学意义(P <0.05),阴性组均优于阳性组;新生儿出生后临床特征比较不存在统计学意义。结论:TPO抗体阳性的孕妇其甲状腺功能紊乱的情况较为明显,并且其并发症的发生率较高,说明TPO抗体阳性会对妊娠结果造成不利的影响。
出处 《深圳中西医结合杂志》 2018年第21期168-169,共2页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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  • 1吴妙琼,刘艳虹,谭晓军,等.妊娠早期单纯性甲状腺自身抗体阳性与不良妊娠的关系[J].广东医学,2013,34(11):1718-1780.
  • 2中华医学会内分泌学分会,中华医学会围产医学分会.妊娠和产后甲状腺疾病诊治指南[J].中华围产医学杂志,2012,15:385-403.
  • 3Nelson D B, Casey B M, McIntire D D, et al. Subsequent pregnancy outcomes in women previously diagnosed with subclinical hypothyroidism[ J]. Am J Perinatol,2014,31 ( 1 ) : 77-84.
  • 4Tudela C M, Casey B M, Mclntire D D, et al. Relationship of subclinical thyroid disease to the incidence of gestational diabetes [ J ]. Obstet Gyneco1,2012,119 ( 5 ) : 983-988.
  • 5Erdogan M, K6senli A, Ganidagli S, et al. Characteristics of anemia in subclinical and overt hypothyroid patients [J]. Endocr J,2012,59 (3) : 213-220.
  • 6Thangaratinam S, Tan A, Knox E, et al. Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence[J]. BMJ,2011,342 : d2616.
  • 7Reid S M, Middleton P, Cossich M C, et al. Interventions for clinical and subclinical hypothyroidism in pregnancy[ J]. Cochrane Database Syst Rev,2010, (7) .. CD007752.
  • 8Karakosta P, Alegakis D, Georgiou V, et al. Thyroid dysfunction and autoantibodies in early pregnancy are associated with increased risk of gestational diabetes and adverse birth outcomes [ J ]. J Clin Endocrinol Metab ,2012,97 ( 12 ) : 4464-4472.
  • 9Nicholson WK,Robinson KA,Smallridge RC,et al. Prevalence ofpostpartum thyroid dysfunction: a quantitative review [J]. Thyroid,2006,16(6)573-582.
  • 10Karakosta P,Alegakis D,Georgiou V,et al. Thyroid dysfunction andautoantibodies in early pregnancy are associated with increased riskof gestational diabetes and adverse birth outcomes [J]. J ClinEndocrinol Metab,2012,97( 12) :4464-4472.

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