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氟尿嘧啶类联合奥沙利铂方案治疗晚期转移性小肠癌的临床研究

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摘要 目的:探讨氟尿嘧啶类联合奥沙利铂方案治疗晚期转移性小肠癌的临床效果。方法:抽取2015年4月~2017年3月86例进行化疗治疗的晚期转移性小肠癌患者,运用随机数表法分为对照组(n=43)与治疗组(n=43),对照组予以奥沙利铂联合卡培他滨进行治疗,治疗组予以氟尿嘧啶联合奥沙利铂进行治疗,观察两组临床治疗效果与不良反应发生情况。结果:治疗组的临床治疗总有效率为86.05%,对照组为83.72%,差异不具有统计学意义(P>0.05);治疗组不良反应总发生率为6.98%,明显低于对照组的25.58%,差异具有统计学意义(P<0.05)。结论:两种治疗方案的临床效果相似,但氟尿嘧啶类联合奥沙利铂方案能够有效降低不良反应发生率,具有较高的临床推广价值。
出处 《北方药学》 2019年第1期31-32,共2页 Journal of North Pharmacy
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