比较多索茶碱与氨茶碱治疗支气管哮喘患者临床效果

Comparison of the Clinical Effects of Doxofylline and Aminophylline in the Treatment of Patients with Bronchial Asthma

目的对多索茶碱以及氨茶碱在支气管哮喘患者中的临床效果进行探讨。方法依照研究方案将我院收治的19例支气管哮喘患者纳入研究,收治时间选取2015年6月至2017年6月入院治疗的患者,并将其设为实验组,予以多索茶碱治疗;同期纳入支气管哮喘患者19例设为对照组,予以氨茶碱治疗。比较两组患者在此次治疗过程中的临床情况,并比较两组患者的治疗效果、肺通气功能变化以及不良反应。结果与对照组对比显示,实验组的总有效率较高,差异明显(P<0.05),有统计学意义;与对照组对比显示,实验组的肺通气功能指标改善情况较优,差异明显(P<0.05),有统计学意义;与对照组对比显示,实验组的不良反应率较低,差异明显(P<0.05),有统计学意义。结论应用多索茶碱对支气管哮喘进行治疗,能够有效改善患者肺部通气功能,安全性高。

Objective To investigate the clinical effects of doxofylline and aminophylline in patients with bronchial asthma. Methods Considering the study of control needs, 19 patients with bronchial asthma were enrolled in the study. All patients were admitted to hospital from June 2015 to June 2017. They were enrolled in the experimental group and treated with doxofylline. 19 patients with bronchial asthma were enrolled in the control group and treated with aminophylline. The clinical status of the two groups of patients during the treatment was compared, and the treatment effects, lung ventilation function changes and adverse reactions were compared between the two groups. Results Compared with the control group, the total effective rate of the experimental group was higher, and the difference was significant(P< 0.05), which was statistically significant. Compared with the control group, the improvement of lung ventilation function index in the experimental group was better, and the difference was obvious.(P< 0.05), statistically significant; compared with the control group, the adverse reaction rate of the experimental group was lower, the difference was significant(P< 0.05), and statistically significant. Conclusion The application of doxofylline in the treatment of bronchial asthma can effectively improve the pulmonary ventilation function of patients with high safety.