中医药精准防治非酒精性脂肪性肝病探讨

Prevention and Treatment of Non-Alcoholic Fatty Liver Disease Based on Precise Medical Treatment

基于中医整体观念、辨证论治,分析中医药防治非酒精性脂肪性肝病的精准医疗研究思路。在中医基础理论指导下,辨识不同体质、人群、易感基因、非酒精性脂肪性肝病的患者,对患者进行准确分型、分层,精准诊断,借助基因组学、代谢组学等方法,运用中医药进行多靶点、多环节、多途径、多层次的整体精准调节、精准预防、精准治疗,对因治疗与对症治疗相结合,提高个体化防治非酒精性脂肪性肝病防治水平。应用现代科学技术和基础研究,发挥中医药全方位、多靶点的优势,对非酒精性脂肪性肝病患者进行个体化有效干预,对明确本病的发病机制、中医药的精准治疗具有的现实意义。

Based on the overall concept of Traditional Chinese Medicine and the Treatment of Syndrome Differentiation,this paper probes the TCM prevention and treatment of non-alcoholic fatty liver disease on the Precise Medical.Under the guidance of the basic theory of TCM,identify different constitution,the crowd,susceptibility genes,nonalcoholic fatty liver disease patients,for patients with accurate classification,stratified,accurate diagnosis,using methods such as genomics,metabolomics,multiple targets,multiple stage with TCM,multi-channel,multi-level integral precision adjustment,accurate precision prevention,treatment,result of treatment of combined with symptomatic treatment,improve the individual prevention and treatment of nonalcoholic fatty liver disease diagnosis and treatment level.Application of modem science and technology and basic research, play the advantages of more comprehensive,targets of Chinese medicine,targeted individualized and effective intervention in patients with NAFLD,to clear the pathogenesis of the disease,the precision of traditional Chinese medicine treatment has the practical significance.