Cantrell五联征四例产前超声特征分析

Value of prenatal ultrasonography in diagnosis of Pentalogy of Cantrell

回顾性分析2012年11月至2017年5月襄阳市第一人民医院诊断的4例Cantrell五联征胎儿产前超声特征。4例均经产前超声和引产后解剖检查确诊,其中3例为不完全型Cantrell五联征,分别为1例高位脐膨出、胸外心、胸骨下段部分缺损、心包部分缺损、单脐动脉并颈背部淋巴水囊肿,1例高位脐膨出、胸外心、胸骨裂、室间隔缺损,1例中位脐膨出、胸外心、胸骨下段部分缺损、室间隔缺损、双侧马蹄足内翻;1例为高位脐膨出、胸外心、胸骨裂并下段缺损、前膈肌及心包部分缺损、全前脑畸形、右侧第12肋骨缺失、室间隔缺损,为完全型Cantrell五联征。胸外和高-中位脐膨出是Cantrell五联征典型产前超声特征,产前超声具有早期重要诊断价值。

Four cases of Pentalogy of Cantrell were diagnosed by prenatal ultrasonography and confirmed by autopsy after labor induction.There were 1 case of complete Pentalogy of Cantrell and 3 cases of incomplete Pentalogy.In 3 cases of incomplete Pentalogy of Cantrell,1 case presented with high umbilical cord prolapse,extraspectoral heart,partial defect of the lower part of the sternum,partial defect of the pericardium,single umbilical artery and cervical lymphatic cyst;1 case presented with high umbilical cord prolapse,extraspectoral heart,thoracic fissure and ventricular septal defect;and 1 case presented with umbilical cord,extraspectoral heart,partial inferior sternal segment defect,ventricular septal defect and bilateral clubfoot varus.In l case of complete Pentalogy of Cantrell,there were high umbilical cord bulge,extraspectoral heart,chest fissure and inferior segment defect,anterior diaphragm and pericardium defect,total forebrain deformity,right 12th ribs loss and ventricular septal defect.Ectopic heart and omphalocele are typical echographic features of Pentalogy of Cantrel and prenatal ultrasonography is of important value in early diagnosis of this congenital malformation.