寨卡病毒感染与器官损伤

Zika virus infection and organ injury

随着近年来寨卡病毒(zikavirus,ZIKA)疫情多地区频繁爆发,ZIKA病毒感染危害逐渐引起全球高度关注。虽然ZIKA病毒的主要危害是孕妇感染所伴随的新生儿头小畸形,但越来越多的证据表明,ZIKA还能引起患者其他系统器官的损伤和危害。现就ZIKA病毒感染患者神经系统、生殖系统、胎儿以及胎盘等器官损伤研究及其机制的新进展进行综述。

Zika virus ( ZIKA) broken out more frequentiy in many areas in recent years and attracted global attention. Although the main hazard of the ZIKA virus is the neonatal microcephaly associated with maternal infection,there is increasing evidence showed that ZIKA can also damage the patients, other systemic organs. This paper summarizes the research progress and the mechanisms of the damage on nervous system, reproductive system,fetus and placenta in patients with ZIKA virus infection.