多囊卵巢综合征和卵巢巧克力囊肿患者血清抗苗勒管激素检测意义分析

Analysis of the Detection of Anti-MüLlerian Hormone in Polycystic Ovary Syndrome and Chocolate Cyst of Ovary

目的研究多囊卵巢综合征和和卵巢巧克力囊肿患者血清抗苗勒管激素检测意义。方法收集2016年1月-2017年5月就诊的2 685例女性临床资料和AMH检测结果,其中包括296例PCOS、65例卵巢巧克力囊肿及2 324例健康体检者,3组年龄均为20～40岁。使用化学发光法检测AMH含量,将3组结果进行统计分析。结果多囊卵巢综合征组AMH水平明显高于对照组[(9. 26±2. 52) ng/m L vs.(5. 78±1. 95) ng/m L],卵巢巧克力囊肿患者AMH值较健康对照组明显下降[(3. 25±0. 78) ng/m L vs.(5. 78±1. 95) ng/m L]。各组AMH水平随着年龄的增长明显下降。结论多囊卵巢综合征患者AMH明显升高,卵巢巧克力囊肿患者AMH明显降低,育龄女性随年龄增加AMH水平逐渐下降。

Objective To study the significance of the detection of anti-Müllerian hormone( AMH) in polycystic ovarysyndrome( PCOS) and chocolate cyst of ovary diseases. Methods Totally 296 cases of PCOS and 65 cases of chocolate cyst of ovary were collected from January 2016 to May 2017 at Jiangsu Province Hospital of TCM,The data included clinical information and AMH value. The healthy physical examination results of 2324 cases were used as controls. All the people were 20-40 years old. AMH was measured by chemiluminescence. The differences were compared in the three groups. Results Compared with controls,the AMH value in PCOS patients was much higher[( 9. 26 ± 2. 52) ng/mL vs.( 5. 78 ± 1. 95) ng/mL],and AMH vaule in chocolate cyst of ovary patients was decreased[( 3. 25 ± 0. 78) ng/mL vs.( 5. 78 ± 1. 95) ng/mL]. The AMH value declined with age growing. Conclusions AMH vaule is increased in PCOS and decreased in chocolate cyst of ovary,the AMH value declined with age growing in women of childbearing age.