原发性失眠症静息态功能磁共振的研究进展

Research advance in resting state fMRI in primary insomnia

原发性失眠是一种常见的睡眠障碍,其发病机制和脑功能的改变仍不明确。随着功能核磁共振的发展,越来越多的人将功能磁共振用于原发性失眠的研究,以期阐明其发病机制。功能磁共振不仅可以记录脑微观结构的变化,还能将脑微观结构变化时相应脑区的功能状态以影像的形式展示出来,使研究及阐明脑微观结构和功能之间的关系成为可能。现就目前原发性失眠静息态功能核磁共振的研究进展进行综述,以期为原发性失眠的进一步研究提供参考。

Primary insomnia is a common sleep disorder, and its pathogenesis and changes in brain function remain unclear. With the development of functional magnetic resonance imaging (fMRI), more and more people use fMRI to study primary insomnia in order to elucidate its pathogenesis. fMRI can not only record the changes of brain microstructures, but also display the functional states of corresponding brain regions in the form of images, which makes it possible to study and clarify the relationship between brain microstructures and functions. This article reviews the research progress of resting-state fMRI in primary insomnia in order to provide reference for further study of primary insomnia.