人类辅助生殖技术后异位妊娠的诱发因素分析

Analysis on Inducing Factors of Ectopic Pregnancy After Assisted Reproductive Technology (ART)

目的 探讨人类辅助生殖技术(ART)后异位妊娠(EP)的诱发因素.方法 收集2016年1月—2017年12月在生殖中心接受ART助孕治疗的1 034 个周期,依据不孕原因分为输卵管因素和非输卵管因素两组,对ART后发生的EP进行分析.结果 1 034 个周期共获得妊娠439 例(42.46%),其中EP 30 例(6.83%).30 例EP患者中,输卵管妊娠29 例(96.67%),宫角妊娠1 例(3.33%);输卵管因素组发生EP 18 例,发生率7.73%,非输卵管因素组发生EP 12 例,发生率5.83%;根据授精方式的不同,输卵管因素和非输卵管因素两组中,体外受精-胚胎移植(IVF-ET)均比卵母细胞内单精子显微注射-胚胎移植(ICSI-ET)的EP发生率高.结论 ART后EP发生率增加,输卵管因素是EP发生的主要诱发因素.

Objective To investigate the inducing factors of the ectopic pregnancy (EP)after assisted reproductive technology (ART).Methods A reproductive review of 1034 cycles was completed on EP after ART from January 2016 to December 2017.1034 cycles were divided into two groups according to infertility reasons: tubal group and non-tubal group.Results Among 1034 treatment cycles,there were 439 pregnancies achieved (42.46%).The incidence of EP was 6.83%(30/439).However,29 cases of tubal pregnancy (96.67%)and 1case of ovarian pregnancy (3.33%).The incidence of EP of tubal group was higher than that of non-tubal group.In the two ways of ART,the incidence of EP of in vitro fertilization-embryo transfer (IVF-ET)was higher than that of intracytoplasmic sperm injection-embryo transfer (ICSI-ET).Conclusion Tubal factor was the major inducing factor for EP after ART treatment.