针刺疗法治疗乳腺癌术后潮热短期和中期有效性的Meta分析

Short-and medium-clinical effect of acupuncture in treating hot flashes in patients with breast cancer: a meta-analysis

目的:运用循证医学的方法,对针刺疗法治疗乳腺癌术后潮热短期和中期有效性进行Meta分析。方法:收集2017年6月30日以前CNKI、CBM、维普、万方、PubMed数据库针刺疗法治疗乳腺癌术后潮热的临床试验资料,用Cochrane系统评价方法对文章进行质量评分,利用Revman5.3软件对多个研究结果的总体效应进行Meta分析,并进行异质性评价。结果:共纳入6篇文献,Meta分析结果示治疗3个月(SMD:-0.36,95%CI:-0.61～-0.10)和6个月(SMD:-0.41,95%CI:-0.64～-0.18)的随访结果都表明针刺组患者的潮热症状改善优于对照组,两组比较差异有统计学意义(P=0.006,P=0.000 5)。结论:在研究设计较完善的临床研究中,针刺对于乳腺癌术后潮热症状改善的短期和中期效果优于对照组。

Objective:To evaluate the short and medium-clinical effect of acupuncture therapy in treating hot flashes in patients with breast cancer by meta-analysis.Methods:This systematic research analyzed all randomized controlled trials (RCTs)relating with the effects of acupuncture treatment for hot flashes of breast cancer patients in the CNKI,CBM,VIP,Wanfang and PubMed (30^th June 2017 ago).The quality of RCTs was assessed by Coehrane systematic review.Multiple overall effects of results were analyzed with metaanalysis,and evaluated systematically by RevMan5.3software.The heterogeneity was evaluated.Results:In the follow-up visit of 3 months (SMD=-0.36,95%CI:-0.61^-0.10)and 6months (SMD=-0.41,95%CI:-0.64^-0.18),acupuncture improved the syndrome systematically (P=0.006,P=0.0005,respectively).Conclusion:The results of clinical researches with high study quality show that acupuncture treatment can significantly improve the syndrome of hot flashes in short-and medium-term in breast cancer patient.