针灸治疗“化疗脑”的理论基础与选穴思路

The theoretical basis and acupoint selection of acupuncture treatment for “chemo brain”

通过临床实践和文献分析,探讨针灸治疗"化疗脑"(CICI)的有效性及可行性,为针灸治疗"化疗脑"提供参考。从传统中医角度,CICI属于"健忘"类病证,其病位在脑,与心肾关系最密切,病机为肾虚髓空,常兼有肝郁气滞,多属本虚标实之证;从现代研究而言,CICI属于认知功能障碍疾病,与大脑皮层及海马区密切相关,针灸能通过调控多种机制发挥神经保护作用,改善认知功能障碍。由此确定针灸处方,以疏肝益肾为治则,兼配以健脑益智的头部腧穴,可采用电针等手段。

Through clinical practice and literature analysis, the effectiveness and feasibility of acupuncture and moxibustion for “chemo brain” (chemotherapy-induced cognitive impairment, CICI) are explored, which provides a theoretical basis of acupuncture and moxibustion for “chemotherapy brain”. From the point view of TCM, CICI isclassified as amnesia-like disease. The location of disease is in brain and it is most closely related to heart and kidney. The pathogenesis is the deficiency of kidney and marrow, often accompanied with stagnation of qi due to depression of liver. It is deficient in root and excessive in superficial. From the point view of modern research, CICI is a cognitive dysfunction disease, which is closely related to the cerebral cortex and hippocampus. Acupuncture can play a neuroprotective role by regulating various mechanisms to improve cognitive dysfunction. The acupuncture prescriptions should focus on regulating liver and nourishing kidney, accompanied with head acupoints to improve brain and intelligence. The electroacupuncture can be applied. Acupuncture has a rich theoretical basis in the treatment of CICI, but there is a lack of research in this area.