摘要
近年来针灸在体外受精中的应用越来越广泛,而2018年5月15日在JAMA杂志发表的"针刺与假针刺对妇女体外受精(in vitro fertilization,IVF)活产率(live birth rate,LBR)影响"一文的研究结论为不支持采用针刺提高IVF的活产率。为了避免国内外学者们对针灸辅助IVF有效性的误解,笔者主要从针刺方案、结局指标和结果解读3个方面剖析并提出疑问,同时对针灸辅助IVF临床研究的未来发展从选择适宜人群、遵循循证医学标准、设计多种针刺方案、设置合理对照及全面分析试验数据等方面提出思考和建议。
In recent years, acupuncture has been used widely as an adjuvant treatment for the in vitro fertilization (IVF). “Effect of Acupuncture vs Sham Acupuncture on Live Births Among Women Undergoing In Vitro Fertilization: A Randomized Clinical Trial ” published in Journal of the American Medical Association (JAMA) on May 15, 2018, the research findings do not support the use of acupuncture to improve the rate of live births among the women undergoing IVF. In order to avoid the misunderstanding of the scholars at home and abroad for the clinical effects of acupuncture on IVF assistance, the authors put forward the doubts after the analysis from the following 3 aspects, including the acupuncture scheme, outcomes and result explanation. Additionally, the thinking and suggestions are proposed for the future development of the clinical trials of acupuncture IVF assistance in terms of selecting the proper participants, being abided by the standards of the evidence-based medicine, designing multi-acupuncture schemes and setting up the rational control, as well as conducting the overall analysis of the trial data.
作者
杨会生
李晓彤
尚洁
许焕芳
尹雅倩
郝鸣昭
房繄恭
YANG Huisheng;LI Xiaotong;SHANG Jie;XU Huanfang;YIN Yaqian;HAO Mingzhao;FANG Yigong(Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences;China Press of Traditional Chinese Medicine)
出处
《中国针灸》
CAS
CSCD
北大核心
2018年第12期1341-1346,共6页
Chinese Acupuncture & Moxibustion
基金
国家自然科学基金面上项目:81674087
"十三五"国家重点研发计划中医药现代化研究专项:2017 YFC 1703603
关键词
体外受精
胚胎移植
活产率
针刺
美国医学会杂志
in vitro fertilization (IVF)
embryo transfer (ET)
live birth rate
acupuncture
JAMA