洁悠神长效抗菌材料在预防小儿肱骨远端骨折术后感染中的应用

Application of jie you shen long-acting antimicrobial material in prevention of pin tract infection in percutaneously pinned pediatric distal humeral fractures

目的探讨长效抗菌材料洁悠神(JUC)预防肱骨远端骨折经皮克氏针固定术后针道感染的临床疗效。方法选取符合标准的160例肱骨远端骨折患儿随机分为两组,每组各80名患儿。所有患儿行闭合复位经皮克氏针内固定术后分别采用JUC或安慰剂喷洒克氏针针尾。无菌敷料包扎后行屈肘位石膏固定。术后4~6周拆除石膏,比较两组患儿针道感染率。结果JUC组克氏针针道感染率为1.25%,细菌培养为金黄色葡萄球菌;安慰剂组感染率为10.00%,其中金黄色葡萄球菌感染7例、铜绿假单胞菌感染1例。JUC组感染率明显低于安慰剂组,且差异有统计学意义(P=0.016)。结论术中使用JUC能有效预防经皮克氏针固定术后针道的感染,明显降低针道感染率。

Objective To evaluate the curative effect of jie you shen (JUC) long-acting antimicrobila material (JUC) in preventing pin tract infection in pediatric distal humeral fractures treated with closed reduction and percutaneous Kirschner pin fixation. Methods A total of 160 pediatric patients were given distal humerus fracture surgery by fixation with percutaneous Kirschner pins. After Kischner pin fixation, the pintails and the affected limbs were sprayed with placebo/JUC first, and then wrapped with gauze immersed with placebo/JUC, followed by immobilization with plaster cast at flexion of the elbow. Pin tract infections were evaluated at the time of plaster removal 4-6 weeks after surgery. Results Postoperative Kirschner pin tract infection rate was 1.25% in JUC group, and Staphylococcus aureus was isolated from one patient. The postoperative Kirschner pin tract infection rate was 10.00% in placebo group, including 7 patients infected with Staphylococcus aureus and one patient with Pseudomonas aeruginosa. The infection rate in the JUC group was significantly lower than that in the control group (P=0.016). Conclusion JUC long-acting antimicrobila material can efficiently decrease postoperative pin tract infection after percutaneous Kirschner pin fixation surgeries in pediatric distal humerus fracture patients receiving closed reduction.